Patient Education

Correlation Between Severe Periodontal Disease and Cancer

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The Journal of Dental Research reports that a review of 19 studies, including 16.6 million participants, revealed significant correlations between periodontal (gum) disease and certain types of cancer. Specifically, participants in studies with periodontal disease had an increased risk of esophageal cancer (39%), pancreatic cancer (35%), colorectal cancer (21%), gastric cancer (13%), and liver cancer (9%). 

The researchers who conducted this meta-analysis stated: “In summary, periodontal diseases, especially severe periodontitis, increase the risk of overall and site-specific gastrointestinal cancers. Interventions to prevent and manage periodontal diseases may reduce the risk of developing gastrointestinal cancers.”

While more research is needed to understand the mechanisms involved with these potential increased risks, patients are advised to see their general dentist and periodontist as directed to help maintain optimal oral health, which is related to overall health and well-being.