Researchers Find Links Between Periodontal Disease and Pancreatic Cancer
Some bacteria and fungi that live in the people’s mouths have been collectively associated with a 3.5 times greater risk of developing pancreatic cancer, according to research published in 2025 in JAMA Oncology.
“Our findings provide new insight into the relationship between the oral microbiome and pancreatic cancer,” explained the lead author of the study, Yixuan Meng, PhD, a postdoctoral fellow at New York University.
According to study co-author Jiyoung Ahn, PhD, “By profiling bacterial and fungal populations in the mouth, oncologists may be able to flag those most in need of pancreatic cancer screening.”
“It is clearer than ever that brushing and flossing your teeth may not only help prevent periodontal disease but may also protect against cancer,” said study co-senior author Richard Hayes, DDS, MPH, PhD. However, Dr. Hayes cautioned that the study established a correlation. Further research is needed to establish cause and effect.
This research reinforces the connection between periodontal disease and other diseases such as cancer.Maintaining optimal oral health is one good way to maintain good overall health.